Resveratrol in Red Wine, Chocolate, Grapes Not Associated With Improved Health – oh no after all the hoopla comes this. The antioxidant resveratrol found in red wine, chocolate and grapes was not associated with longevity or the incidence of cardiovascular disease, cancer and inflammation, according to author: Richard D. Semba, M.D., M.P.H., of the Johns Hopkins University School of Medicine, Baltimore, Md., and colleagues. The ÛÏFrench ParadoxÛ of a low incidence of coronary heart disease despite a diet high in cholesterol and saturated fat in France has been attributed to the regular intake of red wine, in particular, to resveratrol and other polyphenols contained in wine. Some preliminary evidence also suggests that resveratrol may have anti-inflammatory effects, prevent cancer, and decrease blood vessel stiffness. The participants (a sample of 783 men and women 65 years or older) were part of the Aging in the Chianti Region study from 1998 to 2009 in two Italian villages. The authors sought to determine if resveratrol levels achieved through diet were associated with inflammation, cancer, cardiovascular disease, and death. Levels were measured using 24 hour urine collections to look for breakdown products of resveratrol. During nine years of follow-up, 268 participants (34.3 percent) died; of the 639 participants free of cardiovascular disease at enrollment, 174 (27.2 percent) developed cardiovascular disease during the follow-up; and of the 734 participants who were free of cancer at enrollment, 34 (4.6 percent) developed cancer during the follow-up. Urine resveratrol metabolite levels were not associated with death, inflammation, cardiovascular disease or cancer. Discussion: ÛÏThis study suggests that dietary resveratrol from Western diets in community-dwelling older adults does not have a substantial influence on inflammation, cardiovascular disease, cancer, or longevity.Û If you watch the 60 Minutes segment on the 90+ Study, you will also find that people who had two alcoholic drinks of any kind lived longer. Check it out.