Findings Support Role of Vascular Disease in Development of Alzheimer’s Disease
Among adults who entered a study more than 25 years ago, an increasing number of midlife vascular risk factors, such as obesity, high blood pressure, diabetes, high cholesterol and smoking, were associated with elevated levels of brain amyloid (protein fragments linked to Alzheimer’s disease) later in life, according to a study published by JAMA. Rsk factors included body mass index 30 or greater, current smoking, hypertension, diabetes, and total cholesterol 200 mg/dL or greater and were evaluated in models that included age, sex, race, genotype, and educational level.
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